Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681300 | 1.00 | PDE3A (0.34) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL2560842 | 0.80 | PDE3A (0.33) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL1179743 | 0.79 | PDE3A (0.36) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL23772976 | 0.77 | PDE3A (0.35) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL19857181 | 0.77 | PDE3A (0.38) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL2465397 | 0.77 | PDE3A (0.35) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL21734464 | 0.75 | PDE3A (0.34) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL20385875 | 0.73 | LMNA (0.33) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL27952255 | 0.70 | PIK3CB (0.41) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL8587873 | 0.69 | PDE3A (0.34) | PDE3APDE4DSLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321070-A | Virus targeting to hematopoietic stem cells | 麻省理工学院 | 2023-12-29 | — | — | CN | disclosed |
| CN-117018193-A | Use of TIAR inhibitors for the treatment of hepatitis B virus infection | 北京大学 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022058734-A1 | ANTIMICROBIAL AND ANTIVIRAL COATING | PILKINGTON GROUP LIMITED (GB) | 2022-03-24 | — | — | WO | disclosed |
| US-10852123-B2 | Apparatus for critical-dimension localization microscopy | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (US) | 2020-12-01 | — | — | US | disclosed |
| WO-2020160399-A1 | SYSTEMS AND METHODS FOR LIQUID INJECTION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-08-06 | — | — | WO | disclosed |
| US-20200132437-A1 | APPARATUS FOR CRITICAL-DIMENSION LOCALIZATION MICROSCOPY | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE | 2020-04-30 | — | — | US | disclosed |