SCHEMBL2465397

SCHEMBL2465397

C=Cn1ccc(N)nc1=O

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE3A Q14432 3/20 0.35
PDE4D Q08499 1/20 0.35
SLC29A1 Q99808 1/20 0.35
LMNA P02545 3/20 0.35
THRB P10828 1/20 0.35
MTOR P42345 1/20 0.35
MDM2 Q00987 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
CACNA1F O60840 2/20 0.33
ALB P02768 2/20 0.33
MAPT P10636 2/20 0.33
CACNA1D Q01668 2/20 0.33
CACNA1S Q13698 2/20 0.33
CACNA1C Q13936 2/20 0.33
FGFR1 P11362 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1179743 0.82 PDE3A (0.36) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL19857181 0.80 PDE3A (0.38) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL23772976 0.80 PDE3A (0.35) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL19681300 0.77 PDE3A (0.34) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL21925892 0.77 PDE3A (0.34) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL2560842 0.76 PDE3A (0.33) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL8790826 0.72
SCHEMBL278549 0.72 SLC2A1 (0.46) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL28354919 0.71 PDE3A (0.35) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL4595435 0.71 PDE3A (0.33) PDE3APDE4DSLC29A1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119948172-A Methods, kits and systems for nucleic acid end labeling 陈呈尧 2025-05-06 CN claimed
CN-117321218-A Regeneration method and kit of reusable initiators for nucleic acid synthesis 陈呈尧 2023-12-29 CN claimed
CN-111218529-B Primer composition, kit and method for detecting novel coronaviruses 湖南融健生物科技有限公司 2023-06-23 CN claimed
CN-110628925-B Primer, kit and method for detecting clostridium difficile 湖南融健生物科技有限公司 2023-02-24 CN claimed
CN-112391449-B Multifunctional DNA isothermal amplification method with flexible primer design and application thereof 湖南融健基因生物科技有限公司 2021-04-27 CN claimed
CN-112391449-A Multifunctional DNA isothermal amplification method with flexible primer design and application thereof 湖南融健基因生物科技有限公司 2021-02-23 CN claimed
CN-111218529-A Primer composition, kit and method for detecting novel coronavirus 湖南融健基因生物科技有限公司 2020-06-02 CN claimed
CN-110564823-B DNA constant temperature amplification method and kit 湖南融健基因生物科技有限公司 2020-03-31 CN claimed
CN-110628925-A Primer, kit and method for detecting clostridium difficile 湖南融健基因生物科技有限公司 2019-12-31 CN claimed
CN-110564823-A DNA constant temperature amplification method and kit 湖南融健基因生物科技有限公司 2019-12-13 CN claimed
JP-59184211-A None JP disclosed
CN-119948172-A Methods, kits and systems for nucleic acid end labeling 陈呈尧 2025-05-06 CN disclosed
CN-119677865-A Methods, kits and systems for dual labeling of nucleic acids 陈呈尧 2025-03-21 CN disclosed
CN-113272443-B Compositions and methods for genomic DNA and gene expression analysis in single cells 安捷伦科技有限公司 2025-01-10 CN disclosed
CN-118742654-A Enzymatic synthesis of polynucleotides 陈呈尧 2024-10-01 CN disclosed
EP-1125945-B1 REVERSIBLE PHOTOCOUPLING NUCLEIC ACID AND PHOSPHOROAMIDITE JAPAN SCIENCE & TECH CORP (JP) 2003-05-21 EP disclosed
WO-2003040375-A1 COMPOSITIONS AND PROCESSES USING siRNA, AMPHIPATHIC COMPOUNDS AND POLYCATIONS MIRUS CORPORATION (US) 2003-05-15 WO disclosed
US-20020182608-A1 High resolution DNA detection methods and devices ENPLAS AMERICA, INC. 2002-12-05 US disclosed
EP-1125945-A1 REVERSIBLE PHOTOCOUPLING NUCLEIC ACID AND PHOSPHOROAMIDITE Japan Science and Technology Corporation (JP) 2001-08-22 EP disclosed
JP-S59184211-A HIGH-RIGIDITY RESIN COMPOSITION MATSUSHITA ELECTRIC IND CO LTD 1984-10-19 JP disclosed