Styrene

Styrene

SCHEMBL21927

C=CC#N.C=CC=C.C=Cc1ccccc1.CC=C(C)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.46
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
HTT P42858 1/20 0.36
GLA P06280 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 3/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MCL1 Q07820 2/20 0.34
PTGS2 P35354 1/20 0.34
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C9 P11712 1/20 0.32
APEX1 P27695 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4005344 1.00 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL301613 0.97 AKR1C3 (0.49) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL93464 0.91 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL11043969 0.91 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL1126458 0.91 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL10804465 0.89 ALDH1A1 (0.50) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL28022328 0.88 ALDH1A1 (0.45) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL465498 0.88 ALDH1A1 (0.45) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL238869 0.87 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL134355 0.87 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541443-B1 COATED ARTICLES FOR BLOOD COAGULATION TESTING AND METHODS OF PREPARING THE SAME ENICOR GMBH (DE) 2024-04-10 EP claimed
EP-2585535-B2 PACKAGING ELEMENT TEUFELBERGER GMBH (AT) 2023-11-29 EP claimed
EP-3946931-B1 MULTILAYER SHEETS, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECH BV (NL) 2023-06-07 EP claimed
EP-3464430-B1 METHODS OF IMPROVING ADHESION OF NON-DI-(2-ETHYLHEXYL)PHTHALATE POLYVINYL CHLORIDE TO AN ACRYLIC- OR ABS-BASED POLYMER BAXTER INT (US) 2023-04-12 EP claimed
EP-4139524-A1 EXTRACTION OF DELIGNIFIED, CELLULOSE-BASED FIBERS FROM NATURAL PLANT MATERIAL, AND MATERIALS INCORPORATING SUCH FIBERS University of Maryland, College Park (US) 2023-03-01 EP claimed
US-11541649-B2 Methods and formulations for bonding dissimilar materials CAREFUSION 303, INC. (US) 2023-01-03 US claimed
US-20220412002-A1 BAMBOO STRUCTURES, AND METHODS FOR FABRICATION AND USE THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2022-12-29 US claimed
WO-2022050055-A1 MASK MEMBER FOR COLOR MEASUREMENT DEVICE, COLOR MEASUREMENT DEVICE, AND COLOR MEASUREMENT METHOD 大日精化工業株式会社 2022-03-10 WO claimed
US-20210345600-A1 CRYOPRESERVATION OF CELL MONOLAYERS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2021-11-11 US claimed
WO-2021216663-A1 EXTRACTION OF DELIGNIFIED, CELLULOSE-BASED FIBERS FROM NATURAL PLANT MATERIAL, AND MATERIALS INCORPORATING SUCH FIBERS UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2021-10-28 WO claimed
WO-2000020495-A1 HIGH PERFORMANCE PLASTIC PALLETS GENERAL ELECTRIC COMPANY (US) 2000-04-13 WO claimed
EP-0886469-A2 BACTERICIDAL COMPOSITIONS AND ARTICLES CONTAINING THEM Fenchurch Environmental Group Limited (GB) 1998-12-30 EP claimed
WO-1997024925-A2 BACTERICIDAL COMPOSITIONS AND ARTICLES CONTAINING THEM FENCHURCH ENVIRONMENTAL GROUP LIMITED (GB) 1997-07-17 WO claimed
US-5643990-A RESIN WITH CARBON FIBERS FOR MOLDINGS WITH ELECTRICAL AND MECHANICAL PROPERTIES HYPERION CATALYSTS INTERNATIONAL, INC. (US) 1997-07-01 US claimed
EP-0755977-A2 Flame resistant compositions of polycarbonate and monovinylidene aromatic compounds GENERAL ELECTRIC COMPANY (US) 1997-01-29 EP claimed
EP-0310123-B1 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-09-28 EP claimed
US-4877835-A RUBBER-MODIFIED STYRENE, AROMATIC POLYESTER, AROMATIC POLYCARBONATE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-10-31 US claimed
EP-0310123-A2 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-04-05 EP claimed
EP-0043965-B1 PROCESS FOR PRODUCING STAMPINGS HAVING AN INCREASED WHITE FRACTURE EFFECT IN SHEETS OF VINYL CHLORIDE POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-12 EP claimed
EP-0043965-A1 Process for producing stampings having an increased white fracture effect in sheets of vinyl chloride polymers HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210345600-A1 CRYOPRESERVATION OF CELL MONOLAYERS HPSE, CD44, LIPG AKR1C3 4263/4885ALDH1A1 2599/4885TSHR 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.