Styrene

Styrene

SCHEMBL301613

C=CC#N.C=Cc1ccccc1.CC=C(C)C(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.49
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
HTT P42858 1/20 0.38
GLA P06280 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 3/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MCL1 Q07820 2/20 0.36
PTGS2 P35354 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2C9 P11712 1/20 0.33
APEX1 P27695 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL21927 0.97 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL4005344 0.97 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL238869 0.90 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL134355 0.90 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL1830884 0.89 AKR1C3 (0.40) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL1980399 0.88 ALDH1A1 (0.54) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL295031 0.87 ALDH1A1 (0.48) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL93464 0.86 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA
Styrene SCHEMBL2475762 0.86 ALDH1A1 (0.52) AKR1C3ALDH1A1TSHRGLATDP1
Styrene SCHEMBL1126458 0.86 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRHTTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2439747-B1 68 Ga generator ITM ISOTOPEN TECHNOLOGIEN MUENCHEN AG (DE) 2013-09-18 EP claimed
EP-2404941-A1 Method of manufacturing rubbery polymer and rubber reinforced thermoplastic resin composition using the same LG Chem, Ltd. (KR) 2012-01-11 EP claimed
EP-1671323-B1 LIMITED PLAY DATA STORAGE MEDIA AND METHOD FOR LIMITING ACCESS TO DATA THEREON GEN ELECTRIC (US) 2008-08-20 EP claimed
EP-1000966-B1 Chlorinated vinyl chloride resin composition KANEKA CORP (JP) 2005-02-02 EP claimed
EP-0584749-B1 Blends of styrene resin, imide resin and glass reinforcement BASF AG (DE) 1997-05-07 EP claimed
EP-0513535-B1 Glass fibre-reinforced styrene copolymers BASF AG (DE) 1995-08-09 EP claimed
EP-0584749-A2 Blends of styrene resin, imide resin and glass reinforcement BASF Aktiengesellschaft (DE) 1994-03-02 EP claimed
EP-0513535-A1 Glass fibre-reinforced styrene copolymers BASF Aktiengesellschaft (DE) 1992-11-19 EP claimed
US-4965315-A AROMATIC VINYL MONOMER AND VINYL CYANIDE MONOMER, DIENE RUBBER LATEX DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US claimed
US-4199491-A Polyolefin resin composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1980-04-22 US claimed
US-9771470-B2 Rubber polymer and method of preparing the same LG CHEM, LTD. (KR) 2017-09-26 US disclosed
US-20160053099-A1 RUBBER POLYMER AND METHOD OF PREPARING THE SAME LG CHEM, LTD. (KR) 2016-02-25 US disclosed
US-9102827-B2 Thermoplastic resin having high transparency and high impact strength and preventing low-temperature whitening CHEIL INDUSTRIES INC. (KR) 2015-08-11 US disclosed
CN-101161755-B Antifogging surface treatment agent and antifogging resin chip DAICEL POLYMER LTD 2014-07-09 CN disclosed
US-20140142212-A1 Thermoplastic Resin Having High Transparency and High Impact Strength and Preventing Low-Temperature Whitening CHEIL INDUSTRIES INC. (KR) 2014-05-22 US disclosed
EP-0326938-A2 Impact-modified polycarbonate RÖHM GMBH (DE) 1989-08-09 EP disclosed
US-4802769-A PRESSURIZED, SLIT BARREL FOR KNEADING AND EXTRUDING EMULSION GRAFT POLYMERS VEB KOMBINAT POLYGRAPH "WERNER LAMBERZ" LEIPZIG (DE) 1989-02-07 US disclosed
EP-0057845-B1 PROCESS FOR THE PREPARATION OF GRAFT POLYMERS BAYER AG (DE) 1986-10-01 EP disclosed
US-4458046-A BLEND TO IMPROVE HEAT DEFORMATION CHARACTERISTCS ETHYL CORPORATION (US) 1984-07-03 US disclosed
EP-0057845-A2 Process for the preparation of graft polymers BAYER AG (DE) 1982-08-18 EP disclosed