SCHEMBL21928

SCHEMBL21928

O=C1C=CC(=O)N1c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.47
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 2/20 0.46
KMT2A Q03164 1/20 0.46
HPGD P15428 4/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP3A4 P08684 2/20 0.42
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HSP90AA1 P07900 1/20 0.42
CYP1A2 P05177 3/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
MGLL Q99685 9/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400184 1.00 TLR9 (0.47) TLR9ALDH1A1KDM4EKMT2AHPGD
SCHEMBL29634180 1.00 TLR9 (0.47) TLR9ALDH1A1KDM4EKMT2AHPGD
SCHEMBL22399176 0.92 TLR9 (0.48) TLR9ALDH1A1KDM4EKMT2AHSP90AA1
Acetonitrile SCHEMBL28436643 0.92 ALDH1A1 (0.41) TLR9ALDH1A1KDM4EKMT2AHPGD
SCHEMBL30570724 0.86 CYP1A2 (0.46) TLR9ALDH1A1KDM4EKMT2AHPGD
SCHEMBL1552172 0.86 CYP1A2 (0.46) TLR9ALDH1A1KDM4EKMT2AHPGD
SCHEMBL721959 0.84 CYP1A2 (0.47) TLR9ALDH1A1KDM4EKMT2AHPGD
SCHEMBL21972845 0.82 TLR9 (0.39) TLR9ALDH1A1KMT2ATDP1HSP90AA1
SCHEMBL3263559 0.80 ALDH1A1 (0.45) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL19511453 0.78 TLR9 (0.62) TLR9ALDH1A1KDM4EKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 943 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698675-A1 ELECTRONIC BIOSENSORS HAVING METAL-NONMETAL COMPOUND SEMICONDUCTOR NANOBRIDGE ARRAY SemiconBio Inc. (US) 2026-02-25 EP claimed
US-20250241113-A1 FILM, OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE TCL TECHNOLOGY GROUP CORPORATION (CN) 2025-07-24 US claimed
WO-2025068791-A1 NEW FERRITIN-BASED DELIVERY SYSTEM FOR BODIPY MOLECULES DISRUPTIVE TECHNOLOGICAL ADVANCES IN LIFE SCIENCE S.R.L.- SOCIETÀ BENEFIT, IN FORMA ABBREVIATA, D-TAILS S.R.L. SB (IT) 2025-04-03 WO claimed
US-12220420-B2 Combination therapy for cancer treatment GALERA LABS, LLC (US) 2025-02-11 US claimed
WO-2024220344-A1 ELECTRONIC BIOSENSORS HAVING METAL-NONMETAL COMPOUND SEMICONDUCTOR NANOBRIDGE ARRAY ROSWELL ME, INC. (US) 2024-10-24 WO claimed
CN-117647913-A Negative photosensitive resin composition, application thereof, hardening film, preparation thereof and electronic device 深圳市道尔顿电子材料股份有限公司 2024-03-05 CN claimed
CN-117143496-B Water-based epoxy anti-corrosion coating liquid and preparation method thereof 江苏零界科技集团有限公司 2023-12-29 CN claimed
CN-117143496-A Water-based epoxy anti-corrosion coating liquid and preparation method thereof 江苏零界科技集团有限公司 2023-12-01 CN claimed
CN-115262231-B Self-repairing self-cleaning electromagnetic shielding fabric coating and preparation method and application thereof 江南大学 2023-11-21 CN claimed
EP-3632941-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2023-08-23 EP claimed
WO-2005054854-A1 FLUORESCENCE POLARIZATION INSTRUMENTS AND METHODS FOR DETECTION OF EXPOSURE TO BIOLOGICAL MATERIALS BY FLUORESCENCE POLARIZATION IMMUNOASSAY OF SALIVA, ORAL OR BODILY FLUIDS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY NAVAL MEDICAL RESEARCH CENTER (US) 2005-06-16 WO claimed
US-20050095601-A1 Fluorescence polarization instruments and methods for detection of exposure to biological materials by fluorescence polarization immunoassay of saliva, oral or bodily fluids NAVY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2005-05-05 US claimed
WO-2005003376-A2 ANTHRAX ANTIGEN VACCINE CULTURES BY FLUORESCENCE POLARIZATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY NAVAL MEDICAL RESEARCH CENTER, CODE 00L (US) 2005-01-13 WO claimed
US-20040235075-A1 Rapid immunoassay of anthrax protective antigen in vaccine cultures and bodily fluids by fluorescence polarization CULLUM MALFORD E (US) 2004-11-25 US claimed
EP-1335984-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) Biosensor APS (DK) 2003-08-20 EP claimed
US-20020142347-A1 Biosensor BIOSENSOR APS (DK) 2002-10-03 US claimed
WO-2002061096-A1 DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) BIOSENSOR APS (DK) 2002-08-08 WO claimed
US-4942136-A Method for production of fluorescence-labeled Fab' AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-07-17 US claimed
US-4537718-A GLUTATHIONE JOINED BY LINKAGE GROUPS TO A SECTROSCOPIC REPORTER COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1985-08-27 US claimed
US-4207075-A Rabbit immunoglobulin-N-(3-pyrene)-maleimide conjugate for fluorescent immunoassay LIBURDY ROBERT P 1980-06-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12220420-B2 Combination therapy for cancer treatment TXNRD1, TXNRD2, GPX1 TLR9 4653/4885ALDH1A1 153/4885KDM4E 4249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.