Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718047 | 0.93 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| Butyric Acid SCHEMBL1284593 | 0.85 | KMT2A (0.47) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL29634180 | 0.80 | TLR9 (0.47) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL21928 | 0.80 | TLR9 (0.47) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL29400184 | 0.80 | TLR9 (0.47) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL9151931 | 0.77 | DDAH1 (0.41) | — | |
| SCHEMBL890402 | 0.76 | POLB (0.61) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| Acetonitrile SCHEMBL28436643 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL31248316 | 0.73 | TSHR (0.54) | ALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL6024354 | 0.72 | CYP3A4 (0.47) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101156068-B | Method for detecting misfolded proteins and prions | ADLYFE INC | 2015-03-18 | — | — | CN | claimed |
| EP-1412518-B1 | SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BINDING SYSTEMS | NANOGEN RECOGNOMICS GMBH (DE) | 2010-05-12 | — | — | EP | claimed |
| EP-1451366-B1 | MOLECULAR DETECTION SYSTEMS UTILIZING REITERATIVE OLIGONUCLEOTIDE SYNTHESIS | RIBOMED BIOTECHNOLOGIES INC (US) | 2010-03-10 | — | — | EP | claimed |
| US-7541165-B2 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | RIBOMED BIOTECHNOLOGIES, INC. (US) | 2009-06-02 | — | — | US | claimed |
| CN-101156068-A | Method for detecting misfolded proteins and prions | ADLYFE INC (US) | 2008-04-02 | — | — | CN | claimed |
| US-20050026150-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | RIBOMED BIOTECHNOLOGIES, INC. | 2005-02-03 | — | — | US | claimed |
| US-20040175724-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | DESIGNER GENES, INC. | 2004-09-09 | — | — | US | claimed |
| US-20040157257-A1 | Abortive promoter cassettes | RIBOMED BIOTECHNOLOGIES, INC. (US) | 2004-08-12 | — | — | US | claimed |
| EP-1067134-B1 | Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system | NANOTRONICS INC (US) | 2004-07-28 | — | — | EP | claimed |
| US-20040137461-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | DESIGNER GENES, INC. | 2004-07-15 | — | — | US | claimed |
| US-20030099950-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | RIBOMED BIOTECHNOLOGIES, INC. | 2003-05-29 | — | — | US | claimed |
| EP-0620822-B1 | HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM | NANOTRONICS INC (US) | 2001-05-30 | — | — | EP | claimed |
| CN-109791157-A | MEASUREMENT OF PROTEIN EXPRESSION USING REAGENTS WITH BARCODED OLIGONUCLEOTIDE SEQUENCES | 赛卢拉研究公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109310700-A | Treatment of extrapyramidal syndrome with trapidil | 希诺皮亚生物科学公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-104603290-B | For detecting the nuclease protection assays of nucleotide diversity | HTG分子诊断有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-109069425-A | Method and apparatus for preparing liposome by centrifugation | 贝克顿·迪金森公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20040137461-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | DESIGNER GENES, INC. | 2004-07-15 | — | — | US | disclosed |
| US-20040054162-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | RIBOMED BIOTECHNOLOGIES, INC. | 2004-03-18 | — | — | US | disclosed |
| US-20030099950-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | RIBOMED BIOTECHNOLOGIES, INC. | 2003-05-29 | — | — | US | disclosed |
| US-6255083-B1 | IMMOBILIZING TARGET NUCLEIC ACID, COMPLEMENTARY PRIMER AND ONE NUCLEIC ACID POLYMERASE ON SOLID SUPPORT; CONTACTING THE IMMOBILIZED COMPLEX WITH ONE TYPE OF LABELED NUCLEOTIDE TRIPHOSPHATE; DETECTING UNIQUE LABEL RELEASED FROM NUCLEOTIDE | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2001-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054162-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | POLRMT, RNGTT, POLI | ALDH1A1 1772/4885KDM4E 4015/4885KMT2A 1607/4885 |
| US-20050026150-A1 | Molecular detection systems utilizing reiterative oligonucleotide synthesis | POLRMT, RNGTT, POLR1G | ALDH1A1 3904/4885KDM4E 4223/4885KMT2A 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.