Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061920 | 0.76 | BRD9 (0.43) | MAOAMAOBP2RY2CYP1A2CYP3A4 | |
| SCHEMBL23666028 | 0.71 | MAOA (0.34) | MAOAMAOBP2RY2CYP1A2CYP3A4 | |
| SCHEMBL1757151 | 0.67 | HTR2A (0.46) | CYP1A2TSHRPDE4ACYP2C19 | |
| SCHEMBL3519487 | 0.66 | P2RY2 (0.34) | MAOAMAOBP2RY2 | |
| SCHEMBL21931150 | 0.64 | PDE7A (0.38) | CYP2A6 | |
| SCHEMBL21615134 | 0.64 | BRD4 (0.61) | — | |
| SCHEMBL21391494 | 0.63 | KMT2A (0.38) | P2RY2CYP1A2CYP3A4TSHRMAPK1 | |
| SCHEMBL10101243 | 0.63 | NTRK1 (0.31) | — | |
| SCHEMBL21391523 | 0.63 | MEN1 (0.43) | MAOAMAOBP2RY2CYP1A2CYP2A6 | |
| SCHEMBL17464957 | 0.63 | TDP2 (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210222147-A1 | INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF | SANOFI (FR) | 2021-07-22 | — | — | US | disclosed |
| US-20200131555-A1 | INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2020-04-30 | — | — | US | disclosed |