Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35620 | 0.84 | TSHR (0.35) | ALDH1A1MAPTTSHRFAAHSMN1; SMN2 | |
| SCHEMBL1491961 | 0.84 | TSHR (0.35) | ALDH1A1MAPTTSHRFAAHSMN1; SMN2 | |
| SCHEMBL35295 | 0.84 | ECE1 (0.41) | ECE1MAPTMEN1TSHRKMT2A | |
| SCHEMBL389072 | 0.84 | TSHR (0.35) | ALDH1A1MAPTTSHRFAAHSMN1; SMN2 | |
| SCHEMBL7513885 | 0.74 | HTT (0.46) | MAPTMEN1TSHRKMT2ASLC6A5 | |
| SCHEMBL13055391 | 0.71 | TSHR (0.35) | ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL6025227 | 0.71 | ECE1 (0.43) | ECE1ALDH1A1MAPTMEN1TSHR | |
| SCHEMBL21716614 | 0.71 | RAB9A (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL9169954 | 0.70 | FOLH1 (0.56) | FOLH1 | |
| SCHEMBL9167800 | 0.70 | FOLH1 (0.56) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342588-A1 | IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY | Johnson & Johnson Vision Care, Inc. (US) | 2011-07-13 | — | — | EP | claimed |