Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513885 | 0.88 | HTT (0.46) | HTTABCC4MAPTPRMT1EPHX2 | |
| SCHEMBL13055391 | 0.84 | TSHR (0.35) | MAPTTSHR | |
| SCHEMBL2193000 | 0.84 | ECE1 (0.36) | ECE1MAPTFAAHTSHRMEN1 | |
| SCHEMBL6471112 | 0.83 | PRSS1 (0.31) | — | |
| SCHEMBL35664 | 0.78 | — | — | |
| SCHEMBL8513041 | 0.78 | EGLN1 (0.40) | ECE1KDM4EABCC4MAPTFAAH | |
| SCHEMBL21577394 | 0.77 | SMN1; SMN2 (0.41) | TSHRMEN1KMT2ALMNA | |
| SCHEMBL3686778 | 0.77 | — | — | |
| SCHEMBL10722194 | 0.76 | CASP1 (0.40) | ECE1HTTABCC4MAPTEPHX2 | |
| SCHEMBL21577400 | 0.75 | TSHR (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 835 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2026-05-26 | — | — | US | claimed |
| EP-4514596-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| EP-4514596-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2025-03-05 | — | — | EP | claimed |
| US-12116442-B2 | Method for producing silicone hydrogel contact lenses | ALCON INC. (CH) | 2024-10-15 | — | — | US | claimed |
| EP-3481897-B9 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-04-10 | — | — | EP | claimed |
| EP-4146461-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-03-13 | — | — | EP | claimed |
| EP-4304843-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| EP-3481897-B1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-01-03 | — | — | EP | claimed |
| WO-2023209630-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| US-20230350100-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | US | claimed |
| EP-1519760-A1 | INTRAOCULAR LENSES WITH MODIFIED SURFACE | BAUSCH & LOMB INCORPORATED (US) | 2005-04-06 | — | — | EP | claimed |
| US-20050054745-A1 | Process for the synthesis of soluble, high molecular weight polymers | JOHNSON & JOHNSON VISION CARE, INC. | 2005-03-10 | — | — | US | claimed |
| US-20040006386-A1 | Surface modification of functional group-containing intraocular lenses | BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC) (HU) | 2004-01-08 | — | — | US | claimed |
| WO-2004002546-A1 | INTRAOCULAR LENSES WITH MODIFIED SURFACE | BAUSCH & LOMB INCORPORATED (US) | 2004-01-08 | — | — | WO | claimed |
| US-20040006385-A1 | Surface modification of functional group-containing intraocular lenses with catalyst containing reactive polymer system | BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC) (HU) | 2004-01-08 | — | — | US | claimed |
| WO-2004002545-A1 | INTRAOCULAR LENSES WITH MODIFIED SURFACE | BAUSCH & LOMB INCORPORATED (US) | 2004-01-08 | — | — | WO | claimed |
| EP-1095076-A4 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | SUNSOFT CORP (US) | 2002-11-06 | — | — | EP | claimed |
| US-20010044482-A1 | Interpenetrating polymer network hydrophilic hydrogels for contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2001-11-22 | — | — | US | claimed |
| EP-1095076-A1 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | Sunsoft Corporation (US) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002937-A1 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | SUNSOFT CORPORATION (US) | 2000-01-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12638614-B2 | Method for making silicone hydrogel contact lenses | SMCHD1, CRYAA, CRYZ | ECE1 2800/4885HTT 612/4885PLA2G2A 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.