Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258705 | 0.80 | ALDH1A1 (0.42) | TDP1TRPV1CA12CA2CA9 | |
| SCHEMBL932125 | 0.80 | TDP1 (0.40) | TDP1TRPV1CA12CA2CA9 | |
| SCHEMBL11100157 | 0.80 | TDP1 (0.39) | TDP1TRPV1CA12CA2CA9 | |
| SCHEMBL14141191 | 0.80 | TAAR1 (0.54) | TDP1CA12CA2CA9CYP2D6 | |
| SCHEMBL9413635 | 0.80 | ADRA2B (0.44) | CA12CA2CA9ALDH1A1HDAC3 | |
| SCHEMBL24673909 | 0.79 | CA12 (0.39) | CA12CA2CA9ALDH1A1HPGD | |
| SCHEMBL3492989 | 0.78 | KDM4E (0.47) | TDP1TRPV1CA12CA2CA9 | |
| SCHEMBL29534868 | 0.77 | TDP1 (0.55) | TDP1CA2ALDH1A1PTPN1TSHR | |
| SCHEMBL31203 | 0.77 | TDP1 (0.55) | TDP1CA2ALDH1A1PTPN1TSHR | |
| SCHEMBL7066924 | 0.77 | GAA (0.38) | TDP1TRPV1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100432052-C | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2008-11-12 | — | — | CN | claimed |
| CN-1944405-A | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2007-04-11 | — | — | CN | claimed |
| US-20200149077-A1 | METHOD FOR PRODUCING 1,2-AMINO ALCOHOL COMPOUND BY WHOLE CELL TRANSFORMATION | JIANGNAN UNIVERSITY (CN) | 2020-05-14 | — | — | US | disclosed |
| CN-107954916-A | A kind of 5- methoxy-Indole production methods of the Woelm Alumina composite catalyst based on absorption tetrafluoroacetate | 苏州盖德精细材料有限公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-100432052-C | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2008-11-12 | — | — | CN | disclosed |
| CN-1944405-A | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2007-04-11 | — | — | CN | disclosed |