Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932125 | 0.83 | TDP1 (0.40) | TAAR1TDP1TRPV1CA12CA2 | |
| SCHEMBL21930796 | 0.77 | TDP1 (0.41) | GAATDP1TRPV1BUB1CA12 | |
| SCHEMBL8283681 | 0.76 | MEN1 (0.43) | GAATDP1TRPV1CA12CA2 | |
| SCHEMBL7258705 | 0.75 | ALDH1A1 (0.42) | GAATAAR1TDP1TRPV1CA12 | |
| SCHEMBL21486443 | 0.75 | PNMT (0.41) | GAATAAR1ALDH1A1MAPT | |
| SCHEMBL11100157 | 0.75 | TDP1 (0.39) | GAATDP1TRPV1BUB1CA12 | |
| SCHEMBL28341725 | 0.74 | IDO1 (0.42) | GAATDP1TRPV1BUB1CA12 | |
| SCHEMBL11558262 | 0.74 | IDO1 (0.42) | TDP1TRPV1CA12CA2CA9 | |
| SCHEMBL28814441 | 0.74 | GAA (0.32) | GAATAAR1CA12CA2CA9 | |
| SCHEMBL3492989 | 0.73 | KDM4E (0.47) | GAATDP1TRPV1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313718-A2 | INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES | Biotie Therapies Corp. (FI) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002002090-A2 | INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES | BIOTIE THERAPIES CORP. (FI) | 2002-01-10 | — | — | WO | disclosed |