Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194087 | 0.81 | KMT2A (0.52) | KMT2ATSHRLMNASMN1; SMN2MEN1 | |
| SCHEMBL2192568 | 0.77 | TP53 (0.42) | KMT2AMEN1ALDH1A1TP53PABPC1 | |
| SCHEMBL2194340 | 0.75 | MEN1 (0.46) | KMT2ATSHRLMNASMN1; SMN2MEN1 | |
| SCHEMBL15157728 | 0.75 | ALDH1A1 (0.48) | KMT2ATSHRLMNASMN1; SMN2MEN1 | |
| SCHEMBL2218436 | 0.75 | MEN1 (0.44) | KMT2ATSHRLMNAMEN1ALDH1A1 | |
| SCHEMBL2220958 | 0.75 | KMT2A (0.50) | KMT2ASMN1; SMN2MEN1ALDH1A1TP53 | |
| SCHEMBL2217138 | 0.74 | ALDH1A1 (0.45) | KMT2ATSHRLMNAMEN1ALDH1A1 | |
| SCHEMBL2192292 | 0.72 | KMT2A (0.46) | KMT2AMEN1TP53PABPC1RAB9A | |
| SCHEMBL2222060 | 0.72 | TP53 (0.47) | KMT2ALMNASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2193749 | 0.70 | NPC1 (0.45) | KMT2AMEN1ALDH1A1TP53PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519522-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ArQule, Inc. (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082270-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE. INC. (US) | 2011-07-07 | — | — | WO | disclosed |