Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381336 | 0.80 | PTGS2 (0.44) | LMNAMAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL21937103 | 0.80 | PTGS2 (0.44) | LMNAMAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL21936041 | 0.76 | NPC1 (0.45) | LMNAMAPTPKMKMT2AALDH1A1 | |
| SCHEMBL21880199 | 0.76 | NPC1 (0.45) | LMNAMAPTPKMKMT2AALDH1A1 | |
| SCHEMBL27919008 | 0.76 | LMNA (0.41) | ELANELMNAGLAMAPTPOLB | |
| SCHEMBL12479221 | 0.74 | ELANE (0.61) | ELANELMNAMAPTPOLBPKM | |
| SCHEMBL11964668 | 0.74 | LMNA (0.77) | ELANELMNAGLAMAPTPOLB | |
| SCHEMBL29154399 | 0.74 | ELANE (0.61) | ELANELMNAMAPTPOLBPKM | |
| SCHEMBL21936042 | 0.73 | ALDH1A1 (0.46) | ELANELMNAGLAMAPTPOLB | |
| SCHEMBL21936196 | 0.73 | MAPT (0.40) | LMNAMAPTPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020082605-A1 | PYRAZOLYL AZOPHENOL COMPOUND AND SYNTHESIS AND DERIVATION THEREOF | 上海交通大学 | 2020-04-30 | — | — | WO | disclosed |