Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14954535 | 0.87 | NOS1 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL9875849 | 0.81 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL21474503 | 0.79 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL1242056 | 0.75 | NOS1 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL4791379 | 0.75 | NOS1 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL1242058 | 0.75 | NOS1 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL10016260 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL19204651 | 0.67 | — | — | |
| SCHEMBL21936203 | 0.67 | — | — | |
| SCHEMBL2154540 | 0.66 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |