Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471852 | 0.70 | PDE7A (0.48) | IDO1AKR1B1HTR6PSEN1PSEN2 | |
| SCHEMBL1408090 | 0.70 | PDE7A (0.48) | IDO1AKR1B1HTR6PSEN1PSEN2 | |
| SCHEMBL6853483 | 0.70 | PDE7A (0.48) | IDO1AKR1B1HTR6PSEN1PSEN2 | |
| SCHEMBL5479245 | 0.69 | CHRM2 (0.62) | IDO1AKR1B1HTR6PSEN1PSEN2 | |
| SCHEMBL21939397 | 0.66 | AKR1B1 (0.41) | IDO1AKR1B1HTR6MEN1KMT2A | |
| SCHEMBL1722012 | 0.61 | PGR (0.69) | IDO1AKR1B1MEN1KMT2APGR | |
| SCHEMBL29025690 | 0.60 | PGR (0.49) | IDO1AKR1B1MEN1KMT2APGR | |
| SCHEMBL9541565 | 0.60 | AKR1B1 (0.51) | IDO1AKR1B1MEN1KMT2A | |
| SCHEMBL9541587 | 0.60 | PGR (0.45) | AKR1B1PGR | |
| SCHEMBL9540073 | 0.58 | MEN1 (0.45) | IDO1AKR1B1MEN1KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099303-B1 | TREATMENT OF DEGENERATIONS AND LIGHT-INDUCED DAMAGE TO THE RETINA | BIOCODEX (FR) | 2020-04-08 | — | — | EP | disclosed |