Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20562595 | 0.82 | L3MBTL1 (0.37) | SLC6A4HTR2AKCNH2L3MBTL1PYCR1 | |
| SCHEMBL20564011 | 0.82 | PTGDR2 (0.41) | SLC6A4HTR2AKCNH2L3MBTL1ALDH1A1 | |
| SCHEMBL14748067 | 0.79 | CCR5 (0.41) | CCR5CYP2A6SLC6A4HTR2AKCNH2 | |
| SCHEMBL31662903 | 0.79 | SLC6A4 (0.35) | SLC6A4HTR2AKCNH2L3MBTL1PYCR1 | |
| SCHEMBL30994653 | 0.79 | SLC6A4 (0.33) | SLC6A4HTR2AKCNH2L3MBTL1PYCR1 | |
| SCHEMBL15111147 | 0.78 | L3MBTL1 (0.33) | SLC6A4HTR2AKCNH2L3MBTL1PYCR1 | |
| SCHEMBL20563120 | 0.78 | CSNK2A1 (0.42) | SLC6A4HTR2AKCNH2L3MBTL1PYCR1 | |
| SCHEMBL20562760 | 0.77 | PTGDR2 (0.41) | L3MBTL1TDP1PTGER1 | |
| SCHEMBL29737932 | 0.77 | PTGDR2 (0.41) | L3MBTL1TDP1PTGER1 | |
| SCHEMBL682486 | 0.77 | MAPK1 (0.43) | SLC6A4L3MBTL1TDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | CCR5 1083/4885CYP2A6 524/4885SLC6A4 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.