Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.48 |
| ▸ | NPY1R | P25929 | 5/20 | 0.48 |
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3043173 | 0.94 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL2198493 | 0.90 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL2192847 | 0.89 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RDPP4 | |
| SCHEMBL2181939 | 0.89 | DPP7 (0.41) | NPY4RNPY1RNPY2RNPY5RDPP4 | |
| SCHEMBL29688688 | 0.86 | OPRM1 (0.51) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL29914692 | 0.85 | OPRM1 (0.50) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL16670447 | 0.85 | OPRM1 (0.51) | OPRK1OPRM1DPP4DPP7DPP8 | |
| SCHEMBL2193514 | 0.83 | DPP4 (0.42) | OPRK1OPRM1DPP4DPP7DPP8 | |
| SCHEMBL9450511 | 0.83 | DPP4 (0.45) | OPRK1DPP4DPP7DPP8DPP9 | |
| SCHEMBL31590961 | 0.81 | OPRM1 (0.53) | OPRK1OPRM1NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173951-B2 | Carbohydrate-based drug delivery polymers and conjugates thereof | NEKTAR THERAPEUTICS (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150051371-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | NEKTAR THERAPEUTICS (US) | 2015-02-19 | — | — | US | disclosed |
| US-8680263-B2 | Carbohydrate-based drug delivery polymers and conjugates thereof | NEKTAR THERAPEUTICS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | STT3B, STT3A, DDOST | NPY4R 2480/4885NPY1R 3329/4885NPY2R 3255/4885 |
| US-20150051371-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | STT3B, STT3A, DDOST | NPY4R 2480/4885NPY1R 3329/4885NPY2R 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.