Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17573933 | 0.81 | MAOA (0.41) | MAOASLC5A2ALOX5ALDH1A1MGLL | |
| SCHEMBL20226289 | 0.75 | MAOA (0.36) | MAOASLC5A2ALDH1A1MGLLKDM1A | |
| SCHEMBL17433168 | 0.74 | MEN1 (0.41) | MAOAALDH1A1KDM1AHTR2CMEN1 | |
| SCHEMBL18731727 | 0.73 | SLC5A2 (0.36) | MAOASLC5A2ALDH1A1MGLLKDM1A | |
| SCHEMBL20226291 | 0.73 | ALDH1A1 (0.38) | MAOASLC5A2ALDH1A1MGLLKDM1A | |
| SCHEMBL15765759 | 0.72 | KMT2A (0.53) | ALDH1A1HTR2AHTR2CHTR2BHDAC4 | |
| SCHEMBL17413543 | 0.72 | SLC5A2 (0.43) | MAOASLC5A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL17774227 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM1AMEN1NPC1KMT2A | |
| SCHEMBL21880352 | 0.70 | HSD17B1 (0.42) | ALOX5NPC1 | |
| SCHEMBL27948099 | 0.70 | NPC1 (0.48) | MAOASLC5A2ALDH1A1KDM1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636637-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | Forma Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |