Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21880548 | 0.86 | FASN (0.36) | CACNA1HAKR1B1 | |
| SCHEMBL21880532 | 0.86 | FASN (0.36) | CACNA1HAKR1B1 | |
| SCHEMBL21880574 | 0.81 | EPHX2 (0.33) | MAPTTSHREPHX2ALDH1A1NR3C2 | |
| SCHEMBL21880562 | 0.81 | EPHX2 (0.33) | MAPTTSHREPHX2ALDH1A1NR3C2 | |
| SCHEMBL21836819 | 0.72 | EPHX2 (0.46) | MAPTEPHX2NAMPTALDH1A1OPRM1 | |
| SCHEMBL22926341 | 0.70 | HTR7 (0.43) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL17410764 | 0.70 | FASN (0.53) | — | |
| SCHEMBL21880395 | 0.70 | ALDH1A1 (0.43) | TSHRNAMPTALDH1A1L3MBTL1 | |
| SCHEMBL21941785 | 0.70 | ALDH1A1 (0.43) | TSHRNAMPTALDH1A1L3MBTL1 | |
| SCHEMBL21880386 | 0.69 | NAMPT (0.36) | TSHREPHX2NAMPTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636637-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | Forma Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |