Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757398 | 1.00 | RAB9A (0.54) | RAB9APTGDR2MAPTTDP1PRSS1 | |
| SCHEMBL27634073 | 1.00 | RAB9A (0.54) | RAB9APTGDR2MAPTTDP1PRSS1 | |
| Hydrochloric Acid SCHEMBL5490127 | 0.99 | RAB9A (0.53) | RAB9APTGDR2MAPTTDP1PRSS1 | |
| SCHEMBL13545503 | 0.98 | RAB9A (0.56) | RAB9APTGDR2MAPTTDP1PRSS1 | |
| SCHEMBL13282757 | 0.89 | PTGDR2 (0.57) | RAB9APTGDR2MAPTTDP1HPGD | |
| SCHEMBL10382178 | 0.86 | RAB9A (0.70) | RAB9APTGDR2MAPTTDP1HPGD | |
| SCHEMBL10381113 | 0.86 | RAB9A (0.70) | RAB9APTGDR2MAPTTDP1HPGD | |
| SCHEMBL15887757 | 0.85 | MAPT (0.49) | RAB9AMAPTPRSS1HPGDTSHR | |
| SCHEMBL1470608 | 0.85 | KDM4E (0.53) | RAB9APTGDR2MAPTPRSS1HPGD | |
| SCHEMBL1469995 | 0.85 | KDM4E (0.53) | RAB9APTGDR2MAPTPRSS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246792-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2014-08-13 | — | — | EP | disclosed |
| US-7977506-B2 | Amino acid for delivering active materials; bioavailability | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-19 | — | — | US | disclosed |
| US-7151191-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-12-19 | — | — | US | disclosed |
| EP-1246792-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2005-02-16 | — | — | EP | disclosed |
| US-20030149296-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-08-07 | — | — | US | disclosed |
| EP-1246792-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051454-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | RAB9A 2126/4885PTGDR2 1135/4885MAPT 1871/4885 |
| US-20030149296-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | RAB9A 2126/4885PTGDR2 1135/4885MAPT 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.