Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640498 | 0.88 | GABRA1 (0.50) | GABRA1GABRB2SLC7A5BACE1KDM6B | |
| SCHEMBL3664456 | 0.86 | GABRA1 (0.54) | GABRA1GABRB2SLC7A5BACE1KDM6B | |
| SCHEMBL14461290 | 0.84 | SLC7A5 (0.66) | GABRA1GABRB2SLC7A5ALOX15KDM4E | |
| SCHEMBL20299942 | 0.84 | SLC7A5 (0.66) | GABRA1GABRB2SLC7A5ALOX15KDM4E | |
| SCHEMBL29388905 | 0.84 | SLC7A5 (0.66) | GABRA1GABRB2SLC7A5ALOX15KDM4E | |
| SCHEMBL21944056 | 0.81 | PPARA (0.58) | ALOX15PPARDPPARAALOX12PPARG | |
| SCHEMBL17414653 | 0.80 | KDM6B (0.66) | SLC7A5KDM6BALOX15KDM4ERECQL | |
| SCHEMBL1755353 | 0.80 | KDM6B (0.66) | SLC7A5KDM6BALOX15KDM4ERECQL | |
| SCHEMBL17211513 | 0.80 | KDM6B (0.66) | SLC7A5KDM6BALOX15KDM4ERECQL | |
| SCHEMBL30388652 | 0.80 | KDM6B (0.66) | SLC7A5KDM6BALOX15KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10639608-B2 | System, device and method for preparing tracers and transferring materials during radiosynthesis | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2020-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10639608-B2 | System, device and method for preparing tracers and transferring materials during radiosynthesis | TERT, VHL, REV1 | GABRA1 4207/4885GABRB2 4714/4885SLC7A5 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.