Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21945004 | 0.89 | SRD5A2 (0.43) | SRD5A2SRD5A1CYP26A1NR1H2NR1H3 | |
| SCHEMBL21944880 | 0.83 | PPARD (0.43) | MAOBPPARDPPARAPPARGFFAR1 | |
| SCHEMBL21945011 | 0.72 | MAOB (0.50) | MAOBMAOAPPARAFFAR1 | |
| SCHEMBL6242376 | 0.72 | SRD5A2 (0.71) | SRD5A2SRD5A1RXRANR1H2NR1H3 | |
| SCHEMBL21944801 | 0.72 | MAOB (0.43) | MAOBMAOAFFAR1NR4A2 | |
| SCHEMBL12577906 | 0.70 | SRD5A2 (0.62) | SRD5A2SRD5A1MAOBMAOAFOXM1 | |
| SCHEMBL21945000 | 0.70 | SRD5A2 (0.55) | SRD5A2SRD5A1RXRANR1H2NR1H3 | |
| SCHEMBL18002480 | 0.70 | SRD5A2 (0.52) | SRD5A2SRD5A1RXRANR1H2NR1H3 | |
| SCHEMBL6242372 | 0.68 | SRD5A2 (0.68) | SRD5A2RXRANR1H2NR1H3PPARD | |
| SCHEMBL12335444 | 0.68 | SRD5A2 (0.65) | SRD5A2SRD5A1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | SRD5A2 937/4885SRD5A1 764/4885CYP26A1 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.