Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717945 | 0.85 | ALDH1A1 (0.46) | HCAR2ATM | |
| SCHEMBL26698223 | 0.84 | DYRK1A (0.44) | HCAR2ATM | |
| SCHEMBL3721675 | 0.81 | HCAR2 (0.52) | HCAR2P4HTMATM | |
| SCHEMBL13778479 | 0.80 | FFAR1 (0.56) | FFAR1TBXAS1 | |
| SCHEMBL30178455 | 0.80 | CYP4F2 (0.53) | HCAR2ATM | |
| SCHEMBL30684594 | 0.79 | KDM4E (0.47) | FFAR1TBXAS1KEAP1P4HTM | |
| SCHEMBL2433226 | 0.79 | HCAR2 (0.42) | HCAR2TBXAS1ATM | |
| SCHEMBL21895742 | 0.78 | CYP2C19 (0.51) | HCAR2ATM | |
| SCHEMBL5846204 | 0.78 | FFAR1 (0.61) | NPSR1FFAR1KEAP1FFAR4THRA | |
| SCHEMBL18571368 | 0.78 | TBXAS1 (0.45) | FFAR1TBXAS1KEAP1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055298-B1 | MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE | SUTRO BIOPHARMA INC (US) | 2020-04-29 | — | — | EP | disclosed |