SCHEMBL21949397

SCHEMBL21949397

C/C=C1\CC2CCC1CNC2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8996546 0.78 HSD17B10 (0.32)
SCHEMBL8996551 0.78 HSD17B10 (0.32)
SCHEMBL2019477 0.74
SCHEMBL7599216 0.74
SCHEMBL473655 0.74
SCHEMBL7599222 0.74
SCHEMBL21949370 0.68 CHRNB2 (0.32) CHRNB2CHRNA4
Acrylonitrile SCHEMBL28240761 0.67 ALDH1A1 (0.31)
SCHEMBL28168379 0.64 HSD17B10 (0.32)
SCHEMBL8657415 0.60 CCR5 (0.43) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3640247-B1 SYK INHIBITOR AND USE METHOD THEREFOR CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) 2022-01-12 EP disclosed
EP-3640247-A1 SYK INHIBITOR AND USE METHOD THEREFOR Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2020-04-22 EP disclosed