SCHEMBL21950883

SCHEMBL21950883

CCOC(=O)C1=C(C(=O)OCC)C(C)CCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
LMNA P02545 3/20 0.43
ALOX15 P16050 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 5/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 4/20 0.42
CXCR2 P25025 7/20 0.40
HTT P42858 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
GAA P10253 3/20 0.38
POLB P06746 1/20 0.38
CXCR4 P61073 4/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
ALOX12 P18054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5658455 0.87 ALDH1A1 (0.41) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL234027 0.77 KDM4E (0.55) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL28283233 0.77 KDM4E (0.55) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL15415139 0.74 MAPT (0.41) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL12323920 0.74 KDM4E (0.49) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL680908 0.74 KDM4E (0.49) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL416292 0.73 KDM4E (0.41) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL480306 0.73 KDM4E (0.41) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL5608026 0.72 KDM4E (0.59) KDM4EMAPTLMNAALOX15MEN1
SCHEMBL6538246 0.72 KDM4E (0.50) KDM4EMAPTLMNAALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182606-A1 METHOD FOR PRODUCING PROPYLENE COPOLYMER USING CATALYST SYSTEM HAVING IMPROVED COPOLYMERIZATION ACTIVITY HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2024-06-06 US disclosed
EP-4375303-A1 METHOD FOR PRODUCING PROPYLENE COPOLYMER USING CATALYST SYSTEM HAVING IMPROVED COPOLYMERIZATION ACTIVITY Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2024-05-29 EP disclosed
CN-118063652-A Process for producing propylene copolymers using catalyst systems with improved copolymerization activity 韩华道达尔能源有限公司 2024-05-24 CN disclosed
US-20240158543-A1 Solid Catalyst For Producing Polypropylene And Method For Preparation Of Propylene-Derived Polymer HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2024-05-16 US disclosed
EP-4361186-A1 SOLID CATALYST FOR PRODUCING POLYPROPYLENE AND METHOD FOR PREPARATION OF PROPYLENE-DERIVED POLYMER Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2024-05-01 EP disclosed
CN-117924563-A Solid catalyst for preparing polypropylene and method for preparing propylene derivative polymer 韩华道达尔能源有限公司 2024-04-26 CN disclosed
CN-111171195-B Propylene polymerization solid catalyst for reducing VOC and method for producing polypropylene using the same 韩华道达尔能源有限公司 2022-12-27 CN disclosed
US-11434315-B2 Propylene polymerizing solid catalyst for reducing VOC and method of producing polypropylene using same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2022-09-06 US disclosed
US-20200172641-A1 Propylene Polymerizing Solid Catalyst For Reducing VOC and Method Of Producing Polypropylene Using Same HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2020-06-04 US disclosed
EP-3653655-A1 PROPYLENE POLYMERIZING SOLID CATALYST FOR REDUCING VOC AND METHOD OF PRODUCING POLYPROPYLENE USING SAME Hanwha Total Petrochemical Co., Ltd. (KR) 2020-05-20 EP disclosed
CN-111171195-A Propylene polymerization solid catalyst for reducing VOC and method for producing polypropylene using the same 韩华道达尔有限公司 2020-05-19 CN disclosed