Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21950883 | 0.87 | KDM4E (0.43) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28611288 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MAPTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL12323920 | 0.75 | KDM4E (0.49) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL680908 | 0.75 | KDM4E (0.49) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL28283233 | 0.74 | KDM4E (0.55) | ALDH1A1MAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL234027 | 0.74 | KDM4E (0.55) | ALDH1A1MAPTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL1144592 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3456275 | 0.74 | MAPT (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14079850 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL7360757 | 0.73 | MAPT (0.46) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157475-B2 | Diamide invertebrate pest control agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-20040259913-A1 | Diamide invertebrate pest control agents | E. I. DU PONT NEMOURS AND COMPANY | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259913-A1 | Diamide invertebrate pest control agents | DDT, DBF4, CBR1 | ALDH1A1 1119/4885MAPT 3325/4885SMN1; SMN2 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.