⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375600 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL801270 | 0.74 | — | — | |
| SCHEMBL1615800 | 0.72 | CHRNB2 (0.58) | — | |
| SCHEMBL18461960 | 0.72 | — | — | |
| SCHEMBL3909951 | 0.72 | — | — | |
| SCHEMBL19910614 | 0.72 | — | — | |
| SCHEMBL1615790 | 0.72 | — | — | |
| SCHEMBL3907850 | 0.72 | — | — | |
| SCHEMBL3096327 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL11639063 | 0.72 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944752-B2 | Block copolymers for stable micelles | INTEZYNE TECHNOLOGIES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944754-B2 | Block copolymers for stable micelles | INTEZYNE TECHNOLOGIES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170073341-A1 | Benzene Sulfonamide Thiazole and Oxazole Compounds | NOVARTIS AG (CH) | 2017-03-16 | — | — | US | disclosed |
| EP-3106462-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | Novartis AG (CH) | 2016-12-21 | — | — | EP | disclosed |
| US-9499665-B2 | Block copolymers for stable micelles | INTEZYNE TECHNOLOGIES, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160264732-A1 | BLOCK COPOLYMERS FOR STABLE MICELLES | INTEZYNE TECHNOLOGIES, INC. | 2016-09-15 | — | — | US | disclosed |
| EP-2282636-B1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | NOVARTIS AG (CH) | 2016-03-23 | — | — | EP | disclosed |
| US-20160068523-A1 | Benzene Sulfonamide Thiazole and Oxazole Compounds | NOVARTIS AG (CH) | 2016-03-10 | — | — | US | disclosed |
| US-9233956-B2 | Benzene sulfonamide thiazole and oxazole compounds | NOVARTIS AG (CH) | 2016-01-12 | — | — | US | disclosed |
| US-20150368401-A1 | BLOCK COPOLYMERS FOR STABLE MICELLES | INTEZYNE TECHNOLOGIES, INC. | 2015-12-24 | — | — | US | disclosed |
| US-20050222128-A1 | Compounds for the treatment of diseases | PFIZER INC | 2005-10-06 | — | — | US | disclosed |
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | disclosed |
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |
| EP-0628561-B1 | Process for preparing cephalosporin compounds from reactive organic acid derivatives | LUCKY LTD (KR) | 1997-09-03 | — | — | EP | disclosed |
| US-5567813-A | Process for preparing cephalosporin compounds from reactive organic acid derivatives | LUCKY LTD. (KR) | 1996-10-22 | — | — | US | disclosed |
| EP-0628561-A1 | Process for preparing cephalosporin compounds from reactive organic acid derivatives | LUCKY LTD. (KR) | 1994-12-14 | — | — | EP | disclosed |
| US-4311699-A | Aminoacid derivatives of cephalosporin compounds | HASKELL THEODORE H | 1982-01-19 | — | — | US | disclosed |
| US-4267180-A | PENICILLINS AND DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| EP-0015772-A1 | N-(2-((acylaminoacylamino or aminoacylamino)phenyl)-4-hydroxy-5-pyrimidinylcarbonyl)cephalosporin compounds, processes for their production, and compositions containing the same | WARNER-LAMBERT COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |