Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14276786 | 0.81 | TDP1 (0.39) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL76832 | 0.79 | KDM4C (0.41) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL1374814 | 0.77 | DGAT1 (0.52) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL21834933 | 0.77 | KDM4C (0.39) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL4197524 | 0.77 | TDP1 (0.37) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL20295137 | 0.77 | GAA (0.39) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL7771576 | 0.77 | TDP1 (0.37) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL9304597 | 0.77 | APLNR (0.38) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL19154278 | 0.77 | TDP1 (0.37) | TDP1DGAT1CA1CA7CA2 | |
| SCHEMBL16296168 | 0.77 | KDM4C (0.39) | TDP1DGAT1CA1CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081918-A2 | ΒETA-CATENIN AND B-CELL LYMPHOMA 9 (BCL9) INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |