SCHEMBL2195307

SCHEMBL2195307

Fc1ccc2nc(-c3ccc(Cl)cc3)c(Cn3nccn3)n2c1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC2A3 P11169 1/20 0.57
SLC2A4 P14672 1/20 0.57
SLC2A1 P11166 16/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KDM4E B2RXH2 1/20 0.52
HTT P42858 1/20 0.52
ALDH1A1 P00352 1/20 0.51
SIRT5 Q9NXA8 1/20 0.51
GABRA1 P14867 1/20 0.49
GABRB2 P47870 1/20 0.49
SLC2A2 P11168 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2193875 0.92 GABRA1 (0.56) SLC2A3SLC2A4SLC2A1MEN1KMT2A
SCHEMBL2195258 0.89 SLC2A1 (0.66) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL2196219 0.84 SLC2A3 (0.54) SLC2A3SLC2A4SLC2A1MEN1KMT2A
SCHEMBL1691885 0.83 GABRB2 (0.55) SLC2A3SLC2A4SLC2A1MEN1KMT2A
Hydrochloric Acid SCHEMBL1430378 0.83 SLC2A3 (0.55) SLC2A3SLC2A4SLC2A1MEN1KMT2A
SCHEMBL1432526 0.82 SLC2A3 (0.53) SLC2A3SLC2A4SLC2A1MEN1KMT2A
SCHEMBL1432171 0.82 SLC2A3 (0.53) SLC2A3SLC2A4SLC2A1MEN1KMT2A
SCHEMBL2222798 0.82 SLC2A1 (0.61) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL1430221 0.79 KDM4E (0.67) SLC2A1KDM4EHTTGABRA1GABRB2
SCHEMBL1430932 0.78 SLC2A3 (0.56) SLC2A3SLC2A4SLC2A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130289013-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS SUNOVION PHARMACEUTICALS INC. 2013-10-31 US disclosed
US-8497278-B2 Imidazo[1,2-a]pyridine compounds SUNOVION PHARMACEUTICALS INC. (US) 2013-07-30 US disclosed
US-20110166146-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS SUNOVION PHARMACEUTICALS INC. (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166146-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS PAICS, ITPA, DPYD SLC2A3 2212/4885SLC2A4 1848/4885SLC2A1 2033/4885
US-20130289013-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS PAICS, ITPA, DPYD SLC2A3 2212/4885SLC2A4 1848/4885SLC2A1 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.