Diphenyleneiodonium

Diphenyleneiodonium

SCHEMBL219548

c1ccc2c(c1)[I+]c1ccccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 16/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
CYBB P04839 2/20 1.00
NOX5 Q96PH1 2/20 1.00
NOX4 Q9NPH5 2/20 1.00
NOX1 Q9Y5S8 2/20 1.00
NPC1 O15118 2/20 1.00
ALDH1A1 P00352 2/20 1.00
MAPK1 P28482 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
TP53 P04637 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C9 P11712 1/20 1.00
TSHR P16473 1/20 1.00
CYP2C19 P33261 1/20 1.00
THPO P40225 1/20 1.00
STAT6 P42226 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenyleneiodonium SCHEMBL29486373 1.00 GPR3 (1.00) GPR3MEN1KMT2ACYBBNOX5
Diphenyleneiodonium SCHEMBL30150802 0.97 GPR3 (1.00) GPR3MEN1KMT2ACYBBNOX5
Diphenyleneiodonium SCHEMBL10834144 0.97 GPR3 (0.93) GPR3MEN1KMT2ACYBBNOX5
Diphenyleneiodonium SCHEMBL159318 0.97 GPR3 (1.00) GPR3MEN1KMT2ACYBBNOX5
Diphenyleneiodonium SCHEMBL5547280 0.94 GPR3 (0.94) GPR3MEN1KMT2ACYBBNOX5
Diphenyleneiodonium SCHEMBL2057393 0.84 GPR3 (0.73) GPR3MEN1KMT2ACYBBNOX5
SCHEMBL8367212 0.81
Diphenyleneiodonium SCHEMBL3733575 0.80 GPR3 (0.68) GPR3MEN1KMT2ACYBBNOX5
Hydrochloric Acid SCHEMBL8168843 0.77
SCHEMBL795440 0.72 GPR3 (0.54) GPR3MEN1KMT2ACYBBNOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
US-20260098070-A1 SMAGP FUSION MOLECULES AND METHODS OF USE THEREOF DEM BIOPHARMA INC (US) 2026-04-09 US claimed
EP-4646427-A2 SMAGP FUSION MOLECULES AND METHODS OF USE THEREOF DEM Biopharma, Inc. (US) 2025-11-12 EP claimed
US-20250311689-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-09 US claimed
US-20250262167-A1 COMPOUNDS, TARGETS AND PATHWAYS FOR MACROPHAGE MODULATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-08-21 US claimed
WO-2025151443-A1 ENDOXIFEN FOR TREATMENT OF RARE CANCERS ATOSSA THERAPEUTICS, INC. (US) 2025-07-17 WO claimed
EP-3129102-B1 IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF US HEALTH (US) 2025-06-18 EP claimed
WO-2025034879-A1 COMPOSITIONS AND METHODS FOR TARGETING CYTOCHROME P450 REDUCTASE COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2025-02-13 WO claimed
WO-2024148295-A2 SMAGP FUSION MOLECULES AND METHODS OF USE THEREOF DEM BIOPHARMA, INC. (US) 2024-07-11 WO claimed
WO-2024132860-A1 DENTAL COMPOSITION COMPRISING A POLYMERIZATION SHRINKAGE MEDIATOR DENTSPLY DETREY GMBH (DE) 2024-06-27 WO claimed
EP-0765668-A1 Extract of Iridaceas and composition containing it L'OREAL (FR) 1997-04-02 EP claimed
WO-1997009032-A1 UTILIZATION OF AN EXTRACT OF A NON PHOTOSYNTHETIC FILAMENTARY BACTERIUM AND COMPOSITION CONTAINING SUCH EXTRACT L'OREAL (FR) 1997-03-13 WO claimed
WO-1997009056-A1 EXTRACT OF IRIDACEAE AND COMPOSITIONS CONTAINING SUCH EXTRACT L'OREAL (FR) 1997-03-13 WO claimed
EP-0761204-A1 Use of extracts of filamentous, non photosynthetic bacteria and the composition containing them L'OREAL (FR) 1997-03-12 EP claimed
WO-1996031217-A9 INHIBITING RETROVIRAL REPLICATION 1996-11-28 WO claimed
WO-1996031217-A1 INHIBITING RETROVIRAL REPLICATION DUKE UNIVERSITY (US) 1996-10-10 WO claimed
WO-1996010402-A1 MULTI-FACETED METHOD TO REPRESS REPRODUCTION OF LATENT VIRUSES IN HUMANS AND ANIMALS DYKE KNOX VAN (US) 1996-04-11 WO claimed
WO-1996002241-A9 USE OF NITROGEN OXIDE SPECIES AND ADDUCTS TO INHIBIT SKELETAL MUSCLE CONTRACTION 1996-02-29 WO claimed
WO-1996002268-A1 INHIBITION OF VIRUS BY NITRIC OXIDE BRIGHAM AND WOMEN'S HOSPITAL (US) 1996-02-01 WO claimed
WO-1996002241-A1 USE OF NITROGEN OXIDE SPECIES AND ADDUCTS TO INHIBIT SKELETAL MUSCLE CONTRACTION DUKE UNIVERSITY (US) 1996-02-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098070-A1 SMAGP FUSION MOLECULES AND METHODS OF USE THEREOF SELPLG, MPEG1, TNFSF11 GPR3 3705/4885MEN1 2009/4885KMT2A 3885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.