Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605714 | 0.84 | KDM4E (0.58) | ALDH1A1GAAKDM4ESMN1; SMN2LMNA | |
| SCHEMBL5899451 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4ENR4A2SMN1; SMN2 | |
| SCHEMBL6218278 | 0.81 | KDM4E (0.49) | ALDH1A1GAAKDM4ELMNAKCNK2 | |
| SCHEMBL16651686 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GAAKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL1238843 | 0.81 | CYP1A2 (0.54) | ALDH1A1GAASMN1; SMN2LMNACYP1A2 | |
| SCHEMBL8589755 | 0.80 | CCR9 (0.53) | ALDH1A1GAAKDM4ESMN1; SMN2LMNA | |
| SCHEMBL3603041 | 0.80 | PDK1 (0.48) | ALDH1A1GAAKDM4ESMN1; SMN2LMNA | |
| SCHEMBL746589 | 0.78 | MAPT (0.52) | ALDH1A1GAALMNACYP1A2CYP2C9 | |
| SCHEMBL27953738 | 0.78 | KMT2A (0.63) | ALDH1A1GAAKDM4ESMN1; SMN2LMNA | |
| SCHEMBL17042042 | 0.78 | SOS1 (0.44) | ALDH1A1GAAKDM4ELMNAKCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481544-B2 | Antibacterial compositions | BIOTA EUROPE LIMITED (GB) | 2013-07-09 | — | — | US | disclosed |
| US-8389516-B2 | Antibacterial compositions | BIOTA EUROPE LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| EP-2034997-B1 | ANTIBACTERIAL COMPOSITIONS | BIOTA EUROPE LTD (GB) | 2012-10-17 | — | — | EP | disclosed |
| US-20120004221-A1 | Antibacterial Compositions | BIOTA EUROPE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20110263590-A1 | Antibacterial Compositions | BIOTA EUROPE LIMITED (GB) | 2011-10-27 | — | — | US | disclosed |
| US-7977340-B2 | Antibacterial compositions | PROLYSIS LTD. (GB) | 2011-07-12 | — | — | US | disclosed |
| US-20090197877-A1 | Antibacterial Compositions | PROLYSIS LTD. (GB) | 2009-08-06 | — | — | US | disclosed |
| EP-2034997-A1 | ANTIBACTERIAL COMPOSITIONS | Prolysis Limited (GB) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007148093-A1 | ANTIBACTERIAL COMPOSITIONS | PROLYSIS LTD. (GB) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004221-A1 | Antibacterial Compositions | CYCS, COX6C, RPS6 | ALDH1A1 2843/4885GAA 4780/4885KDM4E 3843/4885 |
| US-20090197877-A1 | Antibacterial Compositions | CYCS, COX6C, INTS6 | ALDH1A1 3469/4885GAA 4848/4885KDM4E 4304/4885 |
| US-20110263590-A1 | Antibacterial Compositions | CYCS, COX6C, RPS6 | ALDH1A1 2924/4885GAA 4758/4885KDM4E 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.