Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 2/20 | 0.51 |
| ▸ | FNTB | P49356 | 2/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27503089 | 0.79 | MASP2 (0.52) | IDO1TDO2KMT2AALDH1A1MEN1 | |
| SCHEMBL14741391 | 0.79 | CYSLTR2 (0.49) | IDO1TDO2KMT2AALDH1A1MEN1 | |
| SCHEMBL14691472 | 0.78 | MEN1 (0.54) | FNTAFNTBKMT2AALDH1A1MEN1 | |
| SCHEMBL23750421 | 0.77 | GABBR2 (0.50) | FNTAFNTBF10KMT2AALDH1A1 | |
| SCHEMBL657966 | 0.75 | MEN1 (0.59) | FNTAFNTBKMT2AALDH1A1MEN1 | |
| SCHEMBL8098572 | 0.75 | GABBR2 (0.56) | F10SMN1; SMN2GABBR2GABBR1 | |
| SCHEMBL8595114 | 0.75 | KMT2A (0.54) | IDO1TDO2KMT2AALDH1A1MEN1 | |
| SCHEMBL4994297 | 0.75 | PNMT (0.49) | IDO1TDO2KMT2AALDH1A1MEN1 | |
| SCHEMBL28380583 | 0.75 | F2 (0.52) | F10GABBR2GABBR1TSHR | |
| SCHEMBL9392693 | 0.74 | KMT2A (0.50) | IDO1TDO2KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294718-B1 | NEW DIFLUOROKETAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-04-29 | — | — | EP | disclosed |