SCHEMBL21961

SCHEMBL21961

Cn1c(N)nc2ncn(C)c2c1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 4/20 0.47
ADORA2A P29274 3/20 0.47
PIK3CD O00329 1/20 0.47
POLB P06746 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CNR1 P21554 1/20 0.47
ACHE P22303 1/20 0.47
ADORA1 P30542 1/20 0.47
NTSR1 P30989 1/20 0.47
MC3R P41968 1/20 0.47
NOTUM Q6P988 1/20 0.47
SIRT3 Q9NTG7 1/20 0.47
GDA Q9Y2T3 1/20 0.47
NR2E1 Q9Y466 1/20 0.47
CYP3A4 P08684 3/20 0.45
PMP22 Q01453 3/20 0.45
BLM P54132 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17186276 0.98 ADORA2A (0.46) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL9466617 0.83 ADORA2A (0.38) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL26156362 0.81 ADORA2A (0.37) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL25100649 0.80 ADORA2A (0.47) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL21363373 0.80 TRPA1 (0.37) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL21393459 0.80 ADORA2B (0.49) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL8591403 0.79 KDM4E (0.40) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL7017706 0.79 ADORA2B (0.47) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL31288035 0.79 ADORA2B (0.47) ADORA2BADORA2APIK3CDPOLBADORA3
SCHEMBL21363430 0.78 ADORA2A (0.34) ADORA2BADORA2APIK3CDPOLBADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2789 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 CN claimed
CN-117778530-A Method for adding preset joint to 5' end of single-stranded DNA 清华大学 2024-03-29 CN claimed
CN-115367745-B Tungsten-containing substance hybridization and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2023-11-24 CN claimed
US-20230204604-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-06-29 US claimed
CN-115367726-A Oxygen-doped titanium nitride hybridized and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2022-11-22 CN claimed
CN-115367745-A Tungsten-containing substance hybrid and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2022-11-22 CN claimed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN claimed
WO-2021238912-A1 TRANSITION METAL COMPOUND-HYBRIDIZED AND NITROGEN-DOPED POROUS CARBON MATERIAL AND PREPARATION METHOD THEREFOR 北京化工大学 2021-12-02 WO claimed
US-10968248-B2 Trinucleotide mRNA cap analogs Arcturus, Inc. (US) 2021-04-06 US claimed
CN-1679951-A Medicinal composition for tumor body LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679945-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679936-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679946-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679947-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679944-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1628852-A Anti solid tumor medicine composition KONG QINGZHONG (CN) 2005-06-22 CN claimed
EP-1525224-A1 HYALURONIC ACID DERIVATIVES Jasper Ltd. Liability Co. (US) 2005-04-27 EP claimed
EP-1518854-A1 Substituted 06- benzylguanines and 7- or 9- substituted 8-aza-06-benzylguanines THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) 2005-03-30 EP claimed
WO-2004013182-A1 HYALURONIC ACID DERIVATIVES JASPER LTD LIABILITY CO. (US) 2004-02-12 WO claimed