Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962563 | 1.00 | VNN1 (0.39) | VNN1UBE2NIRAK4LOXNTRK1 | |
| SCHEMBL22020076 | 0.90 | VNN1 (0.39) | VNN1ADORA2AADORA1 | |
| SCHEMBL21962491 | 0.90 | VNN1 (0.39) | VNN1ADORA2AADORA1 | |
| SCHEMBL21962810 | 0.88 | VNN1 (0.39) | VNN1IRAK4LOXLMNATSHR | |
| SCHEMBL22020078 | 0.88 | VNN1 (0.39) | VNN1IRAK4LOXLMNATSHR | |
| SCHEMBL22020081 | 0.86 | HSD11B1 (0.38) | VNN1UBE2NLMNATSHRHTT | |
| SCHEMBL22019142 | 0.85 | VNN1 (0.38) | VNN1IRAK4LMNATSHRHTT | |
| SCHEMBL21962621 | 0.85 | VNN1 (0.38) | VNN1IRAK4LMNATSHRHTT | |
| SCHEMBL21962601 | 0.82 | SCD (0.40) | IRAK4BTKSCDMLYCD | |
| SCHEMBL21962580 | 0.82 | HDAC3 (0.43) | LMNATSHRHTTSMN1; SMN2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |