Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014060 | 0.98 | EPHX2 (0.57) | EPHX2KIF11TGM2NPC1RAB9A | |
| SCHEMBL11590901 | 0.79 | KIF11 (0.59) | EPHX2KIF11TGM2NPC1RAB9A | |
| SCHEMBL6437577 | 0.79 | KIF11 (0.59) | EPHX2KIF11TGM2NPC1RAB9A | |
| SCHEMBL23084253 | 0.79 | EPHX2 (0.59) | EPHX2KIF11TGM2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11253689 | 0.78 | KIF11 (0.58) | EPHX2KIF11TGM2NPC1RAB9A | |
| SCHEMBL3826992 | 0.77 | MAPT (0.60) | RAB9AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27214948 | 0.76 | RAB9A (0.61) | EPHX2KIF11TGM2NPC1RAB9A | |
| SCHEMBL27446924 | 0.76 | EPHX2 (0.55) | EPHX2KIF11TGM2NPC1RAB9A | |
| SCHEMBL1387840 | 0.76 | EPHX2 (0.55) | EPHX2KIF11TGM2NPC1RAB9A | |
| SCHEMBL28014759 | 0.76 | MAPT (0.58) | RAB9AALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220008358-A1 | METHODS FOR MANIPULATING CELL STATE TRANSITIONS IN CANCER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-01-13 | — | — | US | disclosed |
| EP-3880803-A1 | METHODS FOR MANIPULATING CELL STATE TRANSITIONS IN CANCER | Agency for Science, Technology and Research (SG) | 2021-09-22 | — | — | EP | disclosed |
| CN-113302288-A | Methods of controlling cellular state transitions in cancer | 新加坡科技研究局 | 2021-08-24 | — | — | CN | disclosed |
| WO-2020101571-A1 | METHODS FOR MANIPULATING CELL STATE TRANSITIONS IN CANCER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-05-22 | — | — | WO | disclosed |