Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826992 | 0.98 | MAPT (0.60) | MAPTALDH1A1GAANPSR1TDP1 | |
| Iodide SCHEMBL3535855 | 0.97 | MAPT (0.58) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL2288364 | 0.84 | MAPT (0.64) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL1999954 | 0.81 | ALDH1A1 (0.61) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL11593120 | 0.81 | MAPT (0.70) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL12348874 | 0.80 | MAPT (0.55) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL28014060 | 0.78 | EPHX2 (0.57) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL23720127 | 0.78 | L3MBTL1 (0.58) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL27110819 | 0.78 | MAPT (0.57) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL2236573 | 0.77 | MAPT (0.71) | MAPTALDH1A1GAANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540814-A | Cyanoguanidine and its use as antiviral agent | ABBVIE INC | 2015-04-22 | — | — | CN | disclosed |