Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963759 | 0.89 | MEN1 (0.33) | MEN1KMT2ATSHRYAP1TEAD4 | |
| SCHEMBL22015449 | 0.89 | MEN1 (0.33) | MEN1KMT2ATSHRYAP1TEAD4 | |
| SCHEMBL22014798 | 0.89 | MEN1 (0.33) | MEN1KMT2ATSHRYAP1TEAD4 | |
| SCHEMBL24209291 | 0.89 | MEN1 (0.33) | MEN1KMT2ATSHRYAP1TEAD4 | |
| SCHEMBL28923004 | 0.84 | GPR119 (0.33) | MEN1KMT2ATSHRUSP2TP53 | |
| Hydrochloric Acid SCHEMBL22555742 | 0.83 | KMT2A (0.36) | MEN1KMT2ATSHRUSP2TP53 | |
| SCHEMBL21963786 | 0.83 | TP53 (0.40) | MEN1KMT2ATSHRUSP2TP53 | |
| SCHEMBL24209017 | 0.82 | CA12 (0.36) | TSHRALDH1A1GAA | |
| SCHEMBL20898275 | 0.81 | FKBP1A (0.38) | MEN1KMT2ATSHRUSP2TP53 | |
| SCHEMBL20907943 | 0.80 | MEN1 (0.36) | MEN1KMT2ATSHRUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880664-A1 | LOX INHIBITORS | The Institute of Cancer Research: Royal Cancer Hospital (GB) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |