SCHEMBL21963879

SCHEMBL21963879

CC(CC(=O)O)C1CCCC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
ALDH1A1 P00352 2/20 0.38
GPBAR1 Q8TDU6 3/20 0.35
CDC25A P30304 2/20 0.34
UGT2B7 P16662 2/20 0.33
LMNA P02545 1/20 0.33
BLM P54132 1/20 0.33
GLA P06280 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
REN P00797 1/20 0.33
ACE P12821 1/20 0.33
VDR P11473 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
CPB2 Q96IY4 1/20 0.31
APLNR P35414 1/20 0.31
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5708012 0.80 CYP1A2 (0.31) CYP1A2IDH1
SCHEMBL22578916 0.79 IDO1 (0.33) IDO1TDO2
SCHEMBL21963678 0.79 LMNA (0.40) CYP1A2ALDH1A1GPBAR1CDC25AUGT2B7
SCHEMBL5708028 0.78 LMNA (0.32) CYP1A2CDC25ALMNABLMIDH1
SCHEMBL5708004 0.78 NR1H4 (0.30) IDO1TDO2
SCHEMBL5708134 0.78 NR1H4 (0.30) IDO1TDO2
SCHEMBL3270172 0.77 IDO1 (0.35) CYP1A2ALDH1A1SMN1; SMN2ACEIDO1
SCHEMBL5708073 0.77 EP300 (0.33) CDC25ALMNABLMCPB2
SCHEMBL5708140 0.77 RAB9A (0.31)
SCHEMBL30491994 0.77 SHBG (0.35) IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3313362-B1 MUSK COMPOSITIONS AND METHODS OF USE THEREOF TAKASAGO PERFUMERY CO LTD (JP) 2022-02-09 EP claimed
EP-3880163-A1 USE OF 1-ETHYL-4,4-DIMETHYL-CYCLOHEXANE DERIVATIVES AS FRAGRANCES Symrise AG (DE) 2021-09-22 EP claimed
WO-2020098901-A1 USE OF 1-ETHYL-4,4-DIMETHYL-CYCLOHEXANE DERIVATIVES AS FRAGRANCES SYMRISE AG (DE) 2020-05-22 WO claimed
EP-3880163-A1 USE OF 1-ETHYL-4,4-DIMETHYL-CYCLOHEXANE DERIVATIVES AS FRAGRANCES Symrise AG (DE) 2021-09-22 EP disclosed
WO-2020098901-A1 USE OF 1-ETHYL-4,4-DIMETHYL-CYCLOHEXANE DERIVATIVES AS FRAGRANCES SYMRISE AG (DE) 2020-05-22 WO disclosed