Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21965012 | 0.91 | HSD11B1 (0.55) | HSD11B1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL21961586 | 0.81 | CYP3A4 (0.80) | HSD11B1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL21874064 | 0.81 | KMT2A (0.68) | MEN1KMT2ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL21961616 | 0.80 | CYP3A4 (0.78) | HSD11B1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL21964271 | 0.80 | CYP3A4 (0.78) | HSD11B1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL21965003 | 0.78 | CYP3A4 (0.75) | HSD11B1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL21964330 | 0.76 | HSD11B1 (0.69) | HSD11B1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL26022096 | 0.76 | HSD11B1 (0.50) | HSD11B1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL351050 | 0.75 | HSD11B1 (1.00) | HSD11B1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL350439 | 0.75 | HSD11B1 (1.00) | HSD11B1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643703-A1 | EP300/CREBBP INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2020-04-29 | — | — | EP | disclosed |