SCHEMBL21965570

SCHEMBL21965570

c1ccc(-c2nc(-c3ccc4c(c3)c3ccc5c(c6ccccc6n5-c5ccccc5)c3n4-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)nc(-n3c4ccccc4c4ccccc43)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
PTGER4 P35408 1/20 0.37
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
NPY5R Q15761 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
IL1R1 P14778 1/20 0.32
ABCG2 Q9UNQ0 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
HPGD P15428 1/20 0.31
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21965498 1.00 L3MBTL1 (0.41) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL21965602 0.97 L3MBTL1 (0.39) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16451957 0.97 KDM4E (0.42) L3MBTL1KDM4EATMPTGER4NPY5R
SCHEMBL23111038 0.96 KDM4E (0.38) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL26055685 0.96 KDM4E (0.39) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16452143 0.96 KDM4E (0.39) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL26055333 0.95 KDM4E (0.38) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16675155 0.94 L3MBTL1 (0.40) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16451932 0.94 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL18868035 0.94 L3MBTL1 (0.39) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200144512-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200144512-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GDA, SOD1, GALC L3MBTL1 615/4885KDM4E 3566/4885ATM 1867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.