SCHEMBL18868035

SCHEMBL18868035

c1ccc(-c2ccc3c(c2)c2ccc4c(c5ccccc5n4-c4ccccc4)c2n3-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
PTGER4 P35408 1/20 0.35
NR3C1 P04150 1/20 0.33
AVPR1A P37288 1/20 0.33
TSPO P30536 1/20 0.32
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
ABCG2 Q9UNQ0 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23118760 1.00 L3MBTL1 (0.39) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL24549663 0.98 KDM4E (0.37) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL24550180 0.98 KDM4E (0.37) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL15197839 0.97 L3MBTL1 (0.41) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL16675155 0.95 L3MBTL1 (0.40) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL22175249 0.95 KDM4E (0.37) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL16451932 0.95 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL23119058 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL23119062 0.95 L3MBTL1 (0.36) L3MBTL1KDM4EATMPTGER4NR3C1
SCHEMBL23119077 0.95 L3MBTL1 (0.36) L3MBTL1KDM4EATMPTGER4NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569452-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-31 US disclosed
US-11171295-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-11-09 US disclosed
US-20210083195-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-03-18 US disclosed
US-20200194681-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-06-18 US disclosed
US-10615348-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-07 US disclosed
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 US disclosed
US-20190157603-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569452-B2 Organic light-emitting device CRY1, TRPA1, CRY2 L3MBTL1 36/4885KDM4E 4495/4885ATM 1790/4885
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, LIN28A, OR51E2 L3MBTL1 231/4885KDM4E 843/4885ATM 4085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.