Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18461960 | 0.74 | — | — | |
| SCHEMBL25657479 | 0.72 | ALDH1A1 (0.35) | ALDH1A1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL24079402 | 0.72 | — | — | |
| SCHEMBL21203863 | 0.68 | — | — | |
| SCHEMBL20045056 | 0.67 | ALDH1A1 (0.42) | ALDH1A1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL801270 | 0.66 | — | — | |
| SCHEMBL14671182 | 0.65 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL21966916 | 0.64 | — | — | |
| SCHEMBL3096327 | 0.64 | ALDH1A1 (0.39) | ALDH1A1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL19910614 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | CRBN, CBL, STUB1 | ALDH1A1 4548/4885CHRNB2 738/4885CHRNB4 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.