SCHEMBL21966465

SCHEMBL21966465

c1ccc(N(c2ccc3c(c2)sc2ccccc23)c2ccc3sc4c(N(c5ccccc5)c5ccccc5)cccc4c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
ALDH1A1 P00352 3/20 0.38
RAB9A P51151 2/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GPR3 P46089 1/20 0.36
ALOX5 P09917 1/20 0.34
CYP1A2 P05177 1/20 0.33
PTGIR P43119 1/20 0.33
PTPN7 P35236 1/20 0.32
DUSP3 P51452 1/20 0.32
PTPN12 Q05209 1/20 0.32
PTPN22 Q9Y2R2 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ATM Q13315 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19660625 1.00 MAPT (0.38) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL22161087 1.00 MAPT (0.38) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL25891585 1.00 MAPT (0.38) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL21973758 1.00 MAPT (0.38) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL18927657 0.99 MAPT (0.36) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL18927919 0.99 MAPT (0.36) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL22147245 0.96 GPR3 (0.39) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL22161245 0.96 GPR3 (0.39) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL21966643 0.96 ALDH1A1 (0.41) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL21966026 0.96 ALDH1A1 (0.41) MAPTALDH1A1RAB9AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200176685-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-06-04 US disclosed
US-20200144510-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, OR10J3 MAPT 2375/4885ALDH1A1 49/4885RAB9A 2602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.