Sugi Predict

Sugi Predict / Compounds / SCHEMBL22147245

SCHEMBL22147245

SCHEMBL22147245

c1ccc(N(c2ccc3sc4ccccc4c3c2)c2ccc3sc4c(N(c5ccccc5)c5ccccc5)cccc4c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 1/20 0.39
▸ ALOX5 P09917 1/20 0.36
▸ CYP1A2 P05177 2/20 0.35
▸ PTGIR P43119 1/20 0.35
▸ MAPT P10636 5/20 0.34
▸ ALDH1A1 P00352 4/20 0.34
▸ RAB9A P51151 3/20 0.34
▸ HPGD P15428 2/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ PTPN7 P35236 1/20 0.34
▸ DUSP3 P51452 1/20 0.34
▸ PTPN12 Q05209 1/20 0.34
▸ PTPN22 Q9Y2R2 1/20 0.34
▸ TNKS O95271 1/20 0.33
▸ TNKS2 Q9H2K2 1/20 0.33
▸ L3MBTL1 Q9Y468 3/20 0.33
▸ KDM4E B2RXH2 3/20 0.33
▸ ATM Q13315 1/20 0.33
▸ DHODH Q02127 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22161245 1.00 GPR3 (0.39) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL15964370 0.99 GPR3 (0.40) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL21966465 0.96 MAPT (0.38) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL19660625 0.96 MAPT (0.38) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL21973758 0.96 MAPT (0.38) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL22161087 0.96 MAPT (0.38) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL25891585 0.96 MAPT (0.38) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL24700781 0.96 GPR3 (0.40) GPR3ALOX5CYP1A2PTGIRMAPT
SCHEMBL18927921 0.96 ALDH1A1 (0.34) GPR3ALOX5CYP1A2MAPTALDH1A1
SCHEMBL22147241 0.95 ALOX5 (0.39) GPR3ALOX5CYP1A2PTGIRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2021-01-28 — — US disclosed
US-20200203623-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-06-25 — — US disclosed
EP-3670510-A2 BENZO[B]NAPHTHO[2,3-D]FURANYL- OR BENZO[B]NAPHTHO[2,3-D]THIOPHENYL-TRIAZINE COMPOUNDS FOR ORGANIC ELECTRONIC ELEMENTS Duk San Neolux Co., Ltd. (KR) 2020-06-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE1, SLC39A11 GPR3 4860/4885ALOX5 936/4885CYP1A2 4244/4885
US-20200203623-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF GPX1, PIEZO1, ORAI2 GPR3 4392/4885ALOX5 3076/4885CYP1A2 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.