Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.74 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.65 |
| ▸ | BCL2 | P10415 | 1/20 | 0.65 |
| ▸ | BID | P55957 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | POLB | P06746 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GRK2 | P25098 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706086 | 0.71 | MEN1 (1.00) | FABP4MCL1BCL2BIDMEN1 | |
| SCHEMBL21968899 | 0.69 | FABP4 (1.00) | FABP4MCL1BCL2BIDMEN1 | |
| SCHEMBL8328341 | 0.60 | MAPT (0.56) | FABP4MCL1MEN1KMT2APOLB | |
| SCHEMBL8028472 | 0.60 | MAPT (0.51) | FABP4MCL1MEN1KMT2APOLB | |
| SCHEMBL9469352 | 0.59 | MAPT (0.47) | FABP4MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL875286 | 0.58 | MAPT (0.57) | MEN1KMT2AL3MBTL1GAATDP1 | |
| SCHEMBL13554691 | 0.56 | MAPT (0.71) | MEN1KMT2APOLBSMN1; SMN2MAPT | |
| SCHEMBL5262117 | 0.56 | MAPT (0.62) | MEN1KMT2AGAAHPGDSMN1; SMN2 | |
| SCHEMBL6759187 | 0.55 | MAPT (0.65) | MEN1KMT2AGAAHPGDSMN1; SMN2 | |
| SCHEMBL31315669 | 0.55 | MAPT (0.65) | MEN1KMT2AGAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | TICURE LTD. (IL) | 2022-01-25 | — | — | US | disclosed |
| US-20200138779-A1 | FABP4 AS A THERAPEUTIC TARGET IN SKIN DISEASES | TICURE LTD. (IL) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | FABP4, FABP2, FABP1 | FABP4 1/4885MCL1 563/4885BCL2 883/4885 |
| US-20200138779-A1 | FABP4 AS A THERAPEUTIC TARGET IN SKIN DISEASES | FABP4, FABP2, FABP1 | FABP4 1/4885MCL1 563/4885BCL2 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.