SCHEMBL21967534

SCHEMBL21967534

Fc1ccc(Nc2nc(Cl)nc3c2ncn3C2CCCCO2)cc1

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 1/20 0.69
FLT3 P36888 7/20 0.58
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP2C19 P33261 1/20 0.43
PDGFRA P16234 1/20 0.42
CCNE1 P24864 1/20 0.42
CDK2 P24941 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21967328 0.97 YTHDC1 (0.64) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL21967560 0.92 YTHDC1 (0.71) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL21967387 0.91 YTHDC1 (0.70) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL21967870 0.90 YTHDC1 (0.69) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL21967748 0.90 FLT3 (0.72) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL17262750 0.90 YTHDC1 (0.71) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL21967147 0.90 FLT3 (0.60) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL22411499 0.89 YTHDC1 (0.70) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL21967315 0.89 FLT3 (0.59) YTHDC1FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL30677408 0.89 YTHDC1 (0.70) YTHDC1FLT3NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662194-B2 Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-05-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662194-B2 Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress TPMT, MTAP, ATIC YTHDC1 384/4885FLT3 2877/4885NPC1 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.