Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153381 | 0.87 | GAA (0.52) | LIPEGAAWDR5MAPTKDM4E | |
| SCHEMBL2199397 | 0.85 | MEN1 (0.48) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL2200148 | 0.81 | MAPT (0.49) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL4668294 | 0.80 | GAA (0.42) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL13304546 | 0.79 | GAA (0.42) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL14564515 | 0.78 | MAPT (0.46) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL2202643 | 0.78 | CHRM3 (0.44) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL12424051 | 0.77 | WDR5 (0.41) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL2199612 | 0.77 | CHRM3 (0.44) | GAAWDR5MAPTKDM4EHTT | |
| SCHEMBL23367944 | 0.77 | MEN1 (0.56) | GAAMAPTKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977363-B2 | Fungicides/bactericides for plant protection; exhibit a strong fortifying effect in plants; for controlling cereal diseases against Puccinia species, and diseases in viticulture and fruit and vegetable production against Botrytis, Venturia or Alternaria species; low toxicity; tolrerance | BAYER CROPSCIENCE AG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-7977363-B2 | Fungicides/bactericides for plant protection; exhibit a strong fortifying effect in plants; for controlling cereal diseases against Puccinia species, and diseases in viticulture and fruit and vegetable production against Botrytis, Venturia or Alternaria species; low toxicity; tolrerance | BAYER CROPSCIENCE AG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-7977363-B2 | Fungicides/bactericides for plant protection; exhibit a strong fortifying effect in plants; for controlling cereal diseases against Puccinia species, and diseases in viticulture and fruit and vegetable production against Botrytis, Venturia or Alternaria species; low toxicity; tolrerance | BAYER CROPSCIENCE AG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | MRPL21, CBR3, NAT1 | LIPE 1398/4885GAA 1475/4885WDR5 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.