Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LIPE | Q05469 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196885 | 0.87 | LIPE (0.46) | GAALIPERAB9AMAPTMEN1 | |
| SCHEMBL4160088 | 0.87 | GAA (0.53) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL13873519 | 0.81 | MAPT (0.49) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL5188399 | 0.78 | GAA (0.46) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL2199360 | 0.76 | GAA (0.49) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL2199397 | 0.74 | MEN1 (0.48) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL23367943 | 0.74 | MAPT (0.55) | GAARAB9AMAPTMEN1KMT2A | |
| SCHEMBL5163362 | 0.73 | MAPT (0.54) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL23367944 | 0.73 | MEN1 (0.56) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL8578841 | 0.73 | ALDH1A1 (0.47) | GAANPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | MRPL21, CBR3, BRD4 | GAA 1330/4885LIPE 1335/4885NPC1 3695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.