SCHEMBL219689

SCHEMBL219689

NNC(=O)c1cc(Cl)nc(NN)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.49
ALDH1A1 P00352 6/20 0.49
GAA P10253 2/20 0.49
MAPT P10636 4/20 0.44
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
BLM P54132 2/20 0.44
NSD2 O96028 1/20 0.44
ALPL P05186 1/20 0.44
POLB P06746 1/20 0.44
ALPI P09923 1/20 0.44
ALPG P10696 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
RECQL P46063 1/20 0.44
CASP6 P55212 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MPO P05164 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6402681 0.87 KDM4E (0.52) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL476639 0.84 ALDH1A1 (0.43) KDM4EALDH1A1GAAMAPTPOLB
SCHEMBL443826 0.82 ALDH1A1 (0.37) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL2745951 0.79 ALDH1A1 (0.49) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL5480908 0.78 ALDH1A1 (0.57) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL28675327 0.76 KDM4E (0.42) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL30612226 0.74 STAT3 (0.38) KDM4EALDH1A1TDP1CA1CA2
SCHEMBL454489 0.74 STAT3 (0.38) KDM4EALDH1A1TDP1CA1CA2
SCHEMBL11374949 0.72 S1PR2 (0.34) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL1893743 0.71 KDM4E (0.68) KDM4EALDH1A1GAAMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4377368-B1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2025-06-18 EP disclosed
US-20240352178-A1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2024-10-24 US disclosed
EP-4400523-A1 AQUEOUS POLYURETHANE-VINYL POLYMER HYBRID DISPERSION Allnex Austria GmbH (AT) 2024-07-17 EP disclosed
EP-4377368-A1 AQUEOUS POLYURETHANE DISPERSION Allnex Austria GmbH (AT) 2024-06-05 EP disclosed
CN-117642443-A Aqueous polyurethane dispersions 湛新奥地利有限公司 2024-03-01 CN disclosed
WO-2023006502-A1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2023-02-02 WO disclosed
US-8087767-B2 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-03 US disclosed
US-20100273018-A1 AQUEOUS VINYL POLYMER COATING COMPOSITIONS DSM IP ASSETS B.V. 2010-10-28 US disclosed
US-20070251423-A1 Aqueous Vinyl Polymer Coating Compositions DSM IP ASSETS B.V. (NL) 2007-11-01 US disclosed
US-20070211126-A1 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY 2007-09-13 US disclosed
EP-1769039-A1 AQUEOUS VINYL POLYMER COATING COMPOSITIONS DSMIP Assets B.V. (NL) 2007-04-04 EP disclosed
WO-2006007978-A1 AQUEOUS VINYL POLYMER COATING COMPOSITIONS DSM IP ASSETS BV (NL) 2006-01-26 WO disclosed
EP-0341886-B1 Aqueous coating compositions ZENECA RESINS BV (NL) 1994-12-07 EP disclosed
EP-0332326-B1 POLYURETHANE COATING COMPOSITIONS ICI RESINS BV (NL) 1993-03-03 EP disclosed
US-4988762-A Crosslinking coating comprising aziridine-modified addition polymers having pendant ketones or aldehydes; protective coatings; adhesives; imination ICI RESINS B.V. (NL) 1991-01-29 US disclosed
US-4983662-A SELF-CROSSLINKING THROUGH HYDRAZINE OR HYDRAZONE AND CARBONYL FUNCTIONAL GROUPS ICI RESINS B.V. (NL) 1991-01-08 US disclosed
EP-0341886-A2 Aqueous coating compositions ZENECA RESINS BV (NL) 1989-11-15 EP disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed