Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TPMT | P51580 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219689 | 0.84 | KDM4E (0.49) | ALDH1A1MAPTHIF1ACYP1A2S1PR2 | |
| SCHEMBL443826 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MAPTS1PR2KDM4ENPC1 | |
| SCHEMBL5586094 | 0.81 | HCAR3 (0.44) | ALDH1A1TPMTTSHRALOX15HIF1A | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL56204 | 0.80 | TPMT (0.56) | ALDH1A1MAPTTPMTTSHRALOX15 | |
| SCHEMBL15500408 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPTS1PR2GPR35KDM4E | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL7828838 | 0.78 | TPMT (0.54) | ALDH1A1MAPTTPMTTSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL2264628 | 0.78 | TPMT (0.54) | ALDH1A1MAPTTPMTTSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL11071500 | 0.78 | TPMT (0.54) | ALDH1A1MAPTTPMTTSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL27673665 | 0.78 | TPMT (0.54) | ALDH1A1MAPTTPMTTSHRALOX15 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL27653662 | 0.78 | TSHR (0.58) | ALDH1A1MAPTTPMTTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070823-A1 | CLEAR COATING COMPOSITION | 日本ペイントホールディングス株式会社 | 2022-04-07 | — | — | WO | disclosed |
| EP-2410857-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | Merck Sharp & Dohme Corp. (US) | 2012-02-01 | — | — | EP | disclosed |
| CN-1984976-B | Aqueous vinyl polymer coating compositions | DSM IP ASSETS BV | 2011-05-18 | — | — | CN | disclosed |
| WO-2010111058-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME CORP. (US) | 2010-09-30 | — | — | WO | disclosed |
| CN-1984976-A | Aqueous vinyl polymer coating compositions | DSM IP ASSETS BV (NL) | 2007-06-20 | — | — | CN | disclosed |